Appearance... White or yellowish crystalline solid. Or yellowish to orange liquid
Melting point... 86 - 87°C.
Solubility... Slightly soluble in water. Soluble in common organic solvents.
pH value... 9.0 - 10.5
Purity... This can vary widely ( 98% to 20% )
Molecular Weight... 293.33
Composition... N-(2,4-dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methylmethanimidamide; N-methylbis(2,4-xylyliminomethyl)amine.
Amitraz is used as an acaricide to control varroa infestations in honey bees.
As an insecticide on fruit trees and other horticultural crops, where it controls...
pear psylla on pears, whitefly on cotton, tetranychid and eriophyid mites on fruit, citrus, ornamental, and other crops, and it controls both eggs and neonate larvae of cotton bollworm as well as tobacco budworm.
It is also used against pests in mammalian domestic pets where it controls ticks and mange mites. Similarly it controls lice on cattle and pigs.
It is used as a synergist to other insecticides.
Amitraz is an alpha-2 agonist.
30 minutes to 2 hours after ingestion...
GI disturbance: nausea, vomiting
Respiratory and CNS depression (drowsiness, coma)
Bradycardia, hypotension, hypothermia
Rise in liver enzyme activity (transaminases)
CNS depression resolves within 18 hours, other signs and symptoms subside within 24 to 48 hours.
Stomach washing may be considered.
Intubation and assisted ventilation may be required.
Dobutamine hydrochloride may be considered to counteract hypotension and slightly raise heart rate.
Fish... LD50 0.74 ppm (rainbow trout), 0.5 ppm (bluegill).
Bird... Oral LD50 788 mg/kg (bobwhite). Dietary LD50 7000 ppm (mallard).
Rat... Oral LD50 650 mg/kg. Dermal LD50 >1600 mg/kg.
Rabbit... Dermal LD50 >200 mg/kg.
Recommended Protective Clothing
Tightly woven long sleeved shirt and long trousers, nitrile rubber gloves, boots, face shield. Wear clean clothing every day, launder before re-using. Remove contaminated clothing immediately. Wash eyes with water. Wash other affected parts of body with soap and water. If the extent of contamination is unknown, bathe entire body thoroughly, change clothing.
Handling & Storage
Do not store at temperatures below 0°C. Avoid contact with eyes, skin, or clothing. Do not breathe mist, keep the container closed. Wash thoroughly after handling. Do not eat or smoke while handling, do not store with food or animal feeds.
Fire Extinguishing Media... Water, foam, dry powder, CO2.